The strikers have impressed on their return to training this week and may be eased on to the bench to give the manager some more firepower.
MacLean was playing out of his skin earlier in the season without being too prolific in front of goal and his build-up play up front has been a massive loss.
Talbot meanwhile has not played since the play-off final against Hartlepool after a nightmare spell of injury but he could partner the former Rangers star on the bench.
Steve Adams is set to be rested though after Sturrock admitted he was brought back a little too early - Chris Brunt should take his place with Burton O'Brien moving back into the middle alongside Glenn Whelan.
Derby could be tired after a marathon Carling Cup game with Doncaster on Tuesday night but will no doubt be fired up after their penalty shoot-out loss.